The lab was rewarded their first R01 this past month and we couldn't be happier. We are super excited to tackle the role of membrane trafficking during division and how the centrosome may direct that process!
How do ciliated cells utilize their REs and centrosomes to develop into a functional polarized organ? Shown is a model for how REs (green) organize at or around the centrosome (red) and target to the midbody (orange). Aim 1 will determine the spatial and temporal activity of Rab8 and Rab11 and the dependence of this activity on the centrosome. Aim 2 will address whether polarity is formed through RE-targeted vesicle transport during cytokinesis and maintained by spindle positioning.
Lindsay won 3rd place at the International Zebrafish Conference (IZFC) this past week in Madison Wisconsin. We had a great time visiting friends, learning about zebrafish, and presenting our work. Lindsay also gave an oral presentation on her and Erica Colicino's studies testing the role of the cytokinetic bridge in lumen formation. Great Job Lindsay! I can't wait to go next year to the IZFC! Also, my favorite conference companion Bart Hehnly Chang also had a successful flight and Madison trip!
I had a great time in Mt. Snow presenting Lindsay and Erica's study examining the cytokinetic bridge in de novo lumen formation. Both the poster session and oral presentation was fun, and I can't wait to go again. My son Bartlett had fun too and I think its time that we make it friendlier for families to bring their kids to week long meetings. I thought this meeting was a perfect one to bring kids too, it was a nice outdoor setting with lots of stuff for my husband and son to do, which included a petting zoo/farm where I got to make a new little friend! Lets promote young scientists by also supporting their ability to have a happy family life. Those with happy home lives and families are more able to produce great science and thats what we all want.
