Chakraborty A, Dutta A, Dettori LG, Daoud R, Li J, Gonzalez I, Xue X, Hehnly H, Sung P, Bah A, Feng W. Complex interplay between FMRP and DHX9 during DNA replication stress. JBC 2023.
Campana MB, Davis TR, Novak SX, Cleverdon ER, Bates M, Krishnan N, Curtis ER, Childs MD, Pierce MR, Morales-Rodgriguez Y, Sieburg MA, Hehnly H, Luyt LG, Hougland JL. Cellular uptake of a fluorescent ligand reveals Ghrelin O-acyltransferase interacts with extracellular peptides and exhibits unexpected localization for a secretory pathway enzyme. ACS Chem Biol. 2023. PMID:37494676
Aljiboury A*, Eric Ingram*, Nikhila Krishnan*, Favour Ononiwu*, Debadrita Pal*, Julie Manikas, Christopher Taveras, Nicole Hall, Jonah Da Silva, Judy Freshour, and Heidi Hehnly. Rab8-, Rab11-, and Rab35-dependent mechanisms coordinating lumen and cilia formation during Left-Right Organizer development. PLOS Genetics. 2023 *equal contributions. PMID: 37186603
Aljiboury A, Mujcic A, Curtis E, Cammerino T, Magny D, Lan Y, Bates M, Freshour J, Ahmed-Braimeh YH, Hehnly H. Pericentriolar matrix (PCM) integrity relies on Cenexin and Polo-Like Kinase (PLK)1. Molecular Biology of the Cell. 2022. PMID:35609215
Krishnan N, Swoger M, Rathbun LI, Fioramonti PJ, Freshour J, Bates M, Patteson AE, Hehnly H. Rab11 endosomes and Pericentrin coordinate centrosome movement during pre-abscission in vivo. Life Sci Alliance. 2022. PMID:35304423
Swoger M, Gupta S, Charrier EE, Bates M, Hehnly H, Patteson AE. Vimentin Intermediate Filaments Mediate Cell Morphology on Viscoelastic Substrates. ACS App Bio Mater. 2022. PMID:3499547
Riley JF, Fioramonti PJ, Rusnock AK, Hehnly H, Castaneda CA. ALS-Linked mutations impair UBQLN2 stress-induced bimolecular condensate assembly in cells. J Neurochem. 2021. PMID:34129687
Rathbun L, Aljiboury A, Bai X, Hall NA, Manikas J, Amack JD, Bembenek JN, Hehnly H, PLK1- and PLK4-mediated asymmetric mitotic centrosome size and positioning in the early zebrafish embryo. Current Biology. 2020
Rathbun L, Colicino E, Manikas J, O’Connell J, Krishnan N, Reilly N, Coyne S, Erdemci-Tandogan G, Garrastegui A, Freshour J, Santra P, Manning ML, Amack J, Hehnly H. Cytokinetic Bridge Triggers De Novo Lumen Formation In Vivo. Nature Communications. 2020
Bucko PJ, Lombard CK, Rathbun L, Garcia I, Bhat A, Wordeman L, Smith FD, Maly DJ, Hehnly H, Scott JD. Subcellular drug targeting illuminates local kinase action. Elife. 2019 Dec 24;8. PMID:31872801
Colicino EG, Stevens K, Curtis E, Rathbun L, Bates M, Manikas J, Amack J, Freshour J, Hehnly H. Chromosome misalignment is associated with PLK1 activity at cenexin-positive mitotic centrosomes. Molecular Biology of the Cell. 2019 PMID:31042116 *Awarded Cover
Dao TP, Martyniak B, Canning AJ, Lei Y, Colicino EG, Cosgrove MS, Hehnly H, Castañeda CA. ALS-Linked Mutations Affect UBQLN2 Oligomerization and Phase Separation in a Position- and Amino Acid-Dependent Manner. Structure. 2019
Dao TP, Kolaitis RM, Kim HJ, O'Donovan K, Martyniak B, Colicino E, Hehnly H, Taylor JP, Castañeda CA. Ubiquitin Modulates Liquid-Liquid Phase Separation of UBQLN2 via Disruption of Multivalent Interactions. Molecular Cell. 2018
Colicino EG, Garrastegui AM, Freshour J, Santra P, Post DE, Kotula L, Hehnly H. Gravin regulates centrosome function through PLK1. Molecular Biology of the Cell. 2018
Taneja N, Fenix AM, Rathbun L, Millis BA, Tyska MJ, Hehnly H, Burnette DT. Focal adhesions control cleavage furrow shape and spindle tilt during mitosis. Scientific Reports 2016
Vertii A, Ivshina M, Zimmerman W, Hehnly H, Kant S, Doxsey S. The Centrosome Undergoes Plk1-Independent Interphase Maturation during Inflammation and Mediates Cytokine Release. Developmental Cell 2016
Hung H, Hehnly H¥, Doxsey S¥. The mother centriole protein, cenexin, modulates symmetric lumen formation through spindle orientation. Current Biology 2016 (¥) depicts co-corresponding author
Hehnly H*, Canton D*, Bucko P, Langeberg LK, Ogier L, Gelman I, Santana LF, Wordeman L, Scott JD. An Aurora A-Plk1 kinase scaffold depleted in testicular seminomas impacts mitotic spindle orientation in germline stem cells. eLIFE. 2015 (*) depicts co-first authorship
Elisa de Souza E, Hehnly H, Perez AM, Vaz Meirelles G, Costa Smetana JH, Doxsey S, Kobarg J., Human Nek7-interactor RGS2 is required for mitotic spindle organization. Cell Cycle. 2015 Feb 9:0. [Epub ahead of print] PMID: 25664600
Chen CT*, Hehnly H*, Yu Q*, Farkas D, Zheng G, Redick SD, Hung HF, Samtani R, Jurczyk A, Akbarian S, Wise C, Jackson A, Bober M, Guo Y, Lo C, Doxsey S. A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation. Current Biology. 2014 2014 Oct 6;24(19):2327-34. PMID: 25220058 (*) depicts co-first authorship *Current Biology Commentary titled “Pericentrin: critical for spindle orientation.”
Hehnly H and Doxsey S, Rab11 endosomes contribute to mitotic spindle organization and orientation. Developmental Cell. 2014 Mar 10;28(5):497-507. PMID: 24561039 *Awarded Cover Image. *Developmental Cell Commentary titled “Spindlegate: the biological consequences of disrupting traffic.”
Hehnly H, Chen CT, Powers C, Lui HL, and Doxsey S, The Centrosome regulates the Rab11-dependent recycling endosome pathway at appendages of the mother centriole. Current Biology. 2012 Oct 23; 22(20):1944-50. PMID: 22981775 *Featured in Faculty 1000 *Featured in Nature Reviews Molecular Cell Biology
Hehnly H, Xu W, Chen J, and Stamnes M (2010) Cdc42 regulates microtubule-dependent Golgi positioning. Traffic. 11(8): 1067-78; PMID: 20525016 *Awarded Cover Image.
Hehnly H, Longhini K, Chen J, and Stamnes M (2009) Retrograde Shiga toxin trafficking is regulated by ARHGAP21 and Cdc42. Molecular Biology of the Cell. 20(20):4303-12 PMID: 19692570
Hehnly H, Sheff D, Stamnes M (2006) Shiga toxin facilitates its retrograde transport by modifying microtubule dynamics. Molecular Biology of the Cell. 17(10): p.4379-89 PMID: 16885418