January 30, 2020

Getting through January with Hehnly Lab Paella

by Heidi Hehnly in Lab Fun

The end of January is improved by Lab Paella, wine, and way more cheesecake than anyone could ever eat.

January 21, 2020

Visiting University of Rochester Medical College!

by Heidi Hehnly in Research Presentations

I had a great time visiting the University of Rochester Mecial College’s Department of Physiology last week. It was especially great to hang out with John Lueck and his laboratory and hear about all the great science going on in the department! Thanks for letting me visit!

John Lueck and I enjoying a delicious beverage.

January 5, 2020

Subcellular drug targeting illuminates local kinase action

by Heidi Hehnly in Collaborative Work

Paula Bucko, a graduate student in John Scott (Pharmacology, UW), recently published an exciting study titled “Subcellular drug targeting illuminates local kinase action.” We (primarily Lindsay Rathbun, Hehnly lab graduate student and myself) were super excited to help Paula and John out with doing the zebrafish/in vivo studies featured in the paper that shows a novel chemical genetic approach to spatially and temporally inhibit the mitotic kinase PLK1.

You can read the study here and a cool digest here.

zebrafish expressing the SNAP-PACT (magenta) for centrosomal targetted PLK1 inhibition during zebrafish embryonic development.

December 18, 2019

ASCB Washington DC 2019

by Heidi Hehnly in Research Presentations, Lab Fun

Lindsay Rathbun (graduate student), Jessica O’Connell (graduate student), Nikhila Krishnan (graduate student), and Julie Manikas (postbac) all did a great job mixing with scientists and presenting their work at ASCB! Julie Manikas gave a talk to a packed room on cilia formation in the developing zebrafish embryo and the rest of the lab gave poster presentations on centrosome signaling, membrane trafficking, forces required to create a tissue, and cell division during embryogenesis. I even had a guest presenter to present my poster on PLK1 activity at the centrosome, Hehnly Lab Alumni Erica Colicino!

Erica Colicino (Hehnly Lab Alum) presenting on cenexin and PLK1

Julie Manikas presenting on Cilia formation in the developing embryo

Jessica O’Connel presenting on the role of the cytokinesis bridge in Rosette formation.

Lindsay Rathbun presenting her work on the role of the Cytokinetic bridge in lumen formation.

Nikhila presenting on the role of endosomes and the centrosome during cell division.

We also enjoyed a great dinner with collaborators and old friends! It was awesome to hang out with Julia Riley from the Castaneda lab, Hui-Fang Hung and Ana Vertii, old friends from the Doxsey Lab, and Colleen McDowell (Wisconsin).

Julia Riley, Erica Colicino, Heidi Hehnly, and Julie Manikas