A new preprint from the lab!

by Heidi Hehnly in


Check out our new preprint found on bioRxiv titled: Temporal and anteriorly positioned mitotic zones drive asymmetric microtubule patterns needed for Left-Right Organizer development.

This study was a group effort led by postdoc Yan Wu and graduate students Yiling Lan and Favour Ononiwu. We were able to look at #microtubule dynamics in the #zebrafish Left Right Organizer for the first time allowing us to find lots of cool stuff about its development!

You can check it out here: https://www.biorxiv.org/content/10.1101/2024.05.12.593765v1

A teaser of how cool the MT dynamics are during zebrafish KV development.


Check out our new Preprint!

by Heidi Hehnly in ,


The Hehnly Lab’s 1st preprint, led by Lindsay Rathbun with the help of many people including our graduate student Abrar Aljiboury and postbac Julie Manikas, along with Josh Bembenek’s laboratory (University of Michigan with X Bai from the NIH) and Jeff Amack’s laboratory (UPSTATE Medical School, Syracuse NY). We found some crazy large centrosomes in extremely large zebrafish embryo cells that scale with changes in cell size! We didn’t leave out C. elegans either. Check it out here:

PLK1- and PLK4-Mediated asymmetric mitotic centrosome size and positioning in the early zebrafish embryo.

Also check out a zebrafish embryo dividing cells! Microtubules (EMTB-GFP) on left and centrosomes (centrin-GFP) on right.

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