The Hehnly Lab Got our FIRST R01!

by Heidi Hehnly in


The lab was rewarded their first R01 this past month and we couldn't be happier.  We are super excited to tackle the role of membrane trafficking during division and how the centrosome may direct that process!

How do ciliated cells utilize their REs and centrosomes to develop into a functional polarized organ?   Shown is a model for how REs (green) organize at or around the centrosome (red) and target to the midbody (orange).   Aim 1  will determine the spatial and temporal activity of Rab8 and Rab11 and the dependence of this activity on the centrosome.   Aim 2  will address whether polarity is formed through RE-targeted vesicle transport during cytokinesis and maintained by spindle positioning.

How do ciliated cells utilize their REs and centrosomes to develop into a functional polarized organ? Shown is a model for how REs (green) organize at or around the centrosome (red) and target to the midbody (orange).  Aim 1 will determine the spatial and temporal activity of Rab8 and Rab11 and the dependence of this activity on the centrosome.  Aim 2 will address whether polarity is formed through RE-targeted vesicle transport during cytokinesis and maintained by spindle positioning.


Hehnly Laboratory start date July 1st 2015

by Heidi Hehnly in ,


Heidi Hehnly's Laboratory will open its doors this summer on July 1st 2015 at SUNY Upstate Medical School in scenic upstate New York.  The Hehnly lab will focus primarily on the interface between membrane traffic and cytoskeletal dynamics throughout the cell cycle, and how this is important in understanding polarity formation and thus organ development and maintenance. 

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