Hehnly Lab Graduate student Favour Ononiwu killing it with her talk covering cilia, Rab GTPases, and lumen formation!
ASCB Washington DC 2019
Lindsay Rathbun (graduate student), Jessica O’Connell (graduate student), Nikhila Krishnan (graduate student), and Julie Manikas (postbac) all did a great job mixing with scientists and presenting their work at ASCB! Julie Manikas gave a talk to a packed room on cilia formation in the developing zebrafish embryo and the rest of the lab gave poster presentations on centrosome signaling, membrane trafficking, forces required to create a tissue, and cell division during embryogenesis. I even had a guest presenter to present my poster on PLK1 activity at the centrosome, Hehnly Lab Alumni Erica Colicino!
We also enjoyed a great dinner with collaborators and old friends! It was awesome to hang out with Julia Riley from the Castaneda lab, Hui-Fang Hung and Ana Vertii, old friends from the Doxsey Lab, and Colleen McDowell (Wisconsin).
Congrats Ana and Alison on the article titled "New frontiers: discovering cilia‐independent functions of cilia proteins"
The two lives of the centrosome during the cell cycle (A) In interphase, the centrosome functions as a basal body for primary cilia formation. (B) The basal body matures into the spindle poles during mitosis. (C) The centrosome duplicates once per cell cycle, during S phase, and moves to opposite sides of the cell starting at G2 and throughout mitosis. In G0, the centrosome docks at the membrane and templates cilia formation once again.
Ana and Alison have just published a fun review talking about the role of cilia proteins outside of the cilia. Take a peak here: Vertii A et al. EMBO Reports.